The significance of TPSA, free to total PSA ratio and PSA density in prostate carcinoma diagnostics
نویسندگان
چکیده
منابع مشابه
The significance of TPSA, free to total PSA ratio and PSA density in prostate carcinoma diagnostics.
Prostate-specific antigen (PSA) is the one of the most valuable tumor markers for the early detection and management of prostate carcinoma, but not an ideal one because of poor specificity in the case of prostatic hypertrophy and other benign conditions. In order to overcome this drawback some other parameters as is free to total ratio (F/T) PSA and PSA density (PSAD) are introduced. It has bee...
متن کاملRole of Serum Total PSA (Prostate Specific Antigen) and Free to Total PSA Ratio in the Diagnosis of Carcinoma Prostate
The objective of the study was to evaluate and compare the role of total and free/total ratio of serum prostate specific antigen level in diagnosing carcinoma prostate. A cross sectional study was conducted at the Department of Biochemistry, Dhaka Medical College (DMC) with collaboration of the Department of Urology, Dhaka Medical College Hospital (DMCH), Dhaka from July 2008 to June 2009. This...
متن کاملprostate-specific antigen (psa) density and free to total psa ratio in diagnosing prostate cancer with prostate-specific anti¬gen levels of 4.0 ng/ml or less
background: we aimed to value the usefulness of free to total prostate-specific antigen and prostate-specific antigen (psa) density for prostate cancer in the patients with psa levels of 4.0 ng/ml or less. methods: a total of 343 subjects with psa levels of 4.0 ng/ml or less were biopsied. all patients were divided into four groups according to the psa levels: 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, ...
متن کاملCorrelation between the complex PSA/total PSA ratio and the free PSA/total PSA ratio, sensitivity and specificity of both markers for the diagnosis of prostate cancer.
OBJECTIVE To compare the behaviour of the PSAcomplex/PSAtotal percentage (PSAc%) against the PSA free/PSA total (PSAl%) and analyse both markers for their usefulness in diagnosing prostate cancer. MATERIAL AND METHODS We measured total PSA (PSAt), free PSA (PSAl), complex PSA (PSAc), PSAl% and PSAc% levels in 158 patients. Of these, 98 (62%) were biopsied for presenting PSAt≥3 ng/dl and PSAl%...
متن کاملUtility of Free/Total Prostate Specific Antigen (f/t PSA) Ratio in Diagnosis of Prostate Carcinoma
The discovery that PSA exists in serum in both free and complexed forms led to development of immunoassays specific for different PSA forms. This helped in measuring free PSA in the presence of PSA-ACT (PSA-alpha antichymotrypsin), hence it was possible to calculate the percent free PSA or free to total PSA ratio, measurement of which was helpful in reducing the number of unnecessary biopsies s...
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ژورنال
عنوان ژورنال: Acta chirurgica Iugoslavica
سال: 2007
ISSN: 0354-950X,2406-0887
DOI: 10.2298/aci0704105m